Fig. 3
Samples of MR spectra and the diagnostic efficiency of in vivo 1H-MRS. 1H-MRS localization of the volume of interest and spectra acquired from the OV tumor (A) and OV_PTX tumor (B), along with fits and residuals of the fits resulting from LCModel quantification: Cr + PCr (3.03 ppm), GPC + PC (3.21 ppm), MM14 + Lip 13a + Lip 13b + MM12 (1.2–1.4 ppm), MM 09 + Lip 09 (0.9 ppm), MM 20 + Lip 20 (2.0 ppm). The (GPC + PC)/(Cr + PCr) ratio was 1.18 for the OV tumor and 5.45 for the OV_PTX tumor. Receiver operating characteristic curve analysis of in vivo differential metabolite (GPC + PC) for differentiating the OV from OV_PTX groups (C). GPC glycerophosphocholine, PC phosphocholine, Cr creatine, PCr phosphocreatine, Lip lipids, MM macromolecules