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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: In vivo detection of dysregulated choline metabolism in paclitaxel-resistant ovarian cancers with proton magnetic resonance spectroscopy

Fig. 2

In vivo metabolic profile of the PTX-sensitive and PTX-resistant tumors. Cell proliferation of OV and OV_PTX cells treated for 48 h with increasing concentrations of PTX (A). Hematoxylin and eosin staining of subcutaneous tumors showing the more obvious cell atypia and nuclear mitosis in the OV_PTX tumor cells (400 × magnification, scale bars = 20 μm) (B). The frequencies and relative concentrations of metabolite peaks in the OV and OV_PTX groups on in vivo 1H-MRS (C, D). *, P < 0.05. PTX paclitaxel, OV: OVCAR-3

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