Fig. 4From: Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathwayEffect of PPARδ on migration, EMT and angiogenesis of HCC cell. PPARδ agonist GW501516 promoted HCC cells migration and PPARδ antagonist GSK3787 reversed the effect of GW501516 (A, C). GW501516 reduced the expression of E-cadherin, increased the expression of Snail and VEGFA, the antagonist abolished the effect (B, D)Back to article page