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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway

Fig. 1

Differential expression of PPARδ in HCC tissue and HCC cell line. Bioinformatics analysis suggested that PPARδ expression was significantly (p < 0.001) higher in HCC than in normal tissues based on TCGA database and GEO databases (A, B). Immunohistochemical analysis of 4 HCC tissues showed that PPARδ was highly expressed in HCC tissues but was weakly positive in adjacent tissues (p < 0.001) (C). qRT-PCR results suggested the mRNA expression of PPARδ in Bel 7402 (p < 0.001), SMMC-7721 (p < 0.001) and HepG2 cells (p < 0.05) was significantly higher than that of LO2 cell (D). WB results suggested that the protein expression of PPARδ was increased in Bel 7402 (p < 0.001), SMMC-7721 (p < 0.001) and HepG2 cells (p < 0.001) compared with LO2 cell (E)

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Journal of Translational Medicine

ISSN: 1479-5876

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