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Table 3 Univariable and multivariable Cox regression analysis of CSS in training cohort

From: A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

  Univariate Multivariable
HR 95%CI P HR 95%CI P
Age 1.09 1.08–1.1  < 0.001 1.05 1.038–1.063  < 0.001
Race       
 White Reference      
 Black 0.96 0.73–1.26 0.8    
 Othera 0.93 0.68–1.27 0.6    
Sex       
 Male Reference      
 Female 1 0.84–1.18 0.9    
Year of diagnosis       
 2010–2013 Reference      
 2014–2017 0.98 0.81–1.18 0.8    
Histologic type       
 Clear cell Reference    Reference   
 Papillary 0.89 0.68–1.15 0.4 0.852 0.65–1.117 0.2
 Chromophobe 0.6 0.36–0.97 0.038 0.517 0.314–0.851 0.009
 Otherb 2.28 1.9–2.73  < 0.001 0.921 0.717–1.184 0.5
Laterality       
 Left Reference      
 Right 1.13 0.96–1.34 0.15    
T stage 1.69 1.55–1.84  < 0.001 1.831 1.661–2.018  < 0.001
Grade       
 I Reference    Reference   
 II 1.62 1.07–2.45 0.022 1.744 1.148–2.65 0.009
 III 2.07 1.34–3.19 0.001 2.155 1.379–3.368 0.001
 IV 5.64 3.2–9.96  < 0.001 4.397 2.462–7.852  < 0.001
 Unknown 3.99 2.66–5.97  < 0.001 1.777 1.15–2.746 0.01
Surgery       
 No Reference    Reference   
 Local excisionc 0.25 0.19–0.33  < 0.001 0.403 0.297–0.547  < 0.001
 Partial Nephrectomy 0.11 0.08–0.15  < 0.001 0.166 0.117–0.236  < 0.001
 Radical Nephrectomy 0.3 0.25–0.36  < 0.001 0.26 0.194–0.349  < 0.001
Radiotherapy       
 No/unknown Reference    Reference   
 Yes 5.9 2.94–11.87  < 0.001 2.554 1.254–5.2 0.01
Chemotherapy       
 No/unknown Reference      
 Yes 5.29 3.16–8.84  < 0.001 Reference   
Tumors number 1.2 1.11–1.31  < 0.001 1.166 1.068–1.273 0.001
Marriage       
 No Reference      
 Married 0.67 0.56–0.79  < 0.001    
Tumor size 1.01 1–1.01  < 0.001    
  1. aOther includes Asian/Pacific Islander, American Indian/Alaskan Native
  2. bOthers includes the pathological type of RCC is not known
  3. cLocal excision includes cryosurgery, thermal ablation, laser excision