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Table 3 Univariable and multivariable Cox regression analysis of CSS in training cohort

From: A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

 

Univariate

Multivariable

HR

95%CI

P

HR

95%CI

P

Age

1.09

1.08–1.1

 < 0.001

1.05

1.038–1.063

 < 0.001

Race

      

 White

Reference

     

 Black

0.96

0.73–1.26

0.8

   

 Othera

0.93

0.68–1.27

0.6

   

Sex

      

 Male

Reference

     

 Female

1

0.84–1.18

0.9

   

Year of diagnosis

      

 2010–2013

Reference

     

 2014–2017

0.98

0.81–1.18

0.8

   

Histologic type

      

 Clear cell

Reference

  

Reference

  

 Papillary

0.89

0.68–1.15

0.4

0.852

0.65–1.117

0.2

 Chromophobe

0.6

0.36–0.97

0.038

0.517

0.314–0.851

0.009

 Otherb

2.28

1.9–2.73

 < 0.001

0.921

0.717–1.184

0.5

Laterality

      

 Left

Reference

     

 Right

1.13

0.96–1.34

0.15

   

T stage

1.69

1.55–1.84

 < 0.001

1.831

1.661–2.018

 < 0.001

Grade

      

 I

Reference

  

Reference

  

 II

1.62

1.07–2.45

0.022

1.744

1.148–2.65

0.009

 III

2.07

1.34–3.19

0.001

2.155

1.379–3.368

0.001

 IV

5.64

3.2–9.96

 < 0.001

4.397

2.462–7.852

 < 0.001

 Unknown

3.99

2.66–5.97

 < 0.001

1.777

1.15–2.746

0.01

Surgery

      

 No

Reference

  

Reference

  

 Local excisionc

0.25

0.19–0.33

 < 0.001

0.403

0.297–0.547

 < 0.001

 Partial Nephrectomy

0.11

0.08–0.15

 < 0.001

0.166

0.117–0.236

 < 0.001

 Radical Nephrectomy

0.3

0.25–0.36

 < 0.001

0.26

0.194–0.349

 < 0.001

Radiotherapy

      

 No/unknown

Reference

  

Reference

  

 Yes

5.9

2.94–11.87

 < 0.001

2.554

1.254–5.2

0.01

Chemotherapy

      

 No/unknown

Reference

     

 Yes

5.29

3.16–8.84

 < 0.001

Reference

  

Tumors number

1.2

1.11–1.31

 < 0.001

1.166

1.068–1.273

0.001

Marriage

      

 No

Reference

     

 Married

0.67

0.56–0.79

 < 0.001

   

Tumor size

1.01

1–1.01

 < 0.001

   
  1. aOther includes Asian/Pacific Islander, American Indian/Alaskan Native
  2. bOthers includes the pathological type of RCC is not known
  3. cLocal excision includes cryosurgery, thermal ablation, laser excision
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Journal of Translational Medicine

ISSN: 1479-5876

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