Skip to main content

Table 2 Univariable and multivariable Cox regression analysis of OS in training cohort

From: A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

  Univariate Multivariable
HR 95%CI P HR 95%CI P
Age 1.09 1.08–1.09  < 0.001 1.048 1.041–1.056  < 0.001
Race       
 White Reference    Reference   
 Black 1.1 0.95–1.26 0.2 1.168 1.011–1.35 0.035
 Othera 0.82 0.68–0.98 0.031 0.919 0.763–1.107 0.4
Sex       
 Male Reference    Reference   
 Female 0.9 0.81–0.99 0.023 0.783 0.707–0.868  < 0.001
Year of diagnosis       
 2010–2013 Reference      
 2014–2017 1.01 0.91–1.12 0.9    
Histologic type       
 Clear cell Reference    Reference   
 Papillary 0.91 0.78–1.06 0.2 0.837 0.717–0.975 0.023
 Chromophobe 0.74 0.57–0.95 0.017 0.678 0.525–0.876 0.003
 Otherb 2.59 2.34–2.86  < 0.001 1.122 0.979–1.287 0.1
Laterality       
 Left Reference      
 Right 1.01 0.92–1.11 0.9    
 T stage 1.22 1.15–1.29  < 0.001 1.23 1.134–1.335  < 0.001
Grade       
 I Reference    Reference   
 II 1.04 0.86–1.26 0.7 1.132 0.935–1.371 0.2
 III 1.17 0.95–1.43 0.14 1.279 1.034–1.584 0.024
 IV 2.34 1.68–3.27  < 0.001 2.241 1.598–3.143  < 0.001
 Unknown 2.6 2.17–3.12  < 0.001 1.097 0.895–1.344 0.375
Surgery       
 No Reference    Reference   
 Local excisionc 0.28 0.24–0.33  < 0.001 0.408 0.348–0.48  < 0.001
 Partial Nephrectomy 0.14 0.12–0.16  < 0.001 0.227 0.189–0.272  < 0.001
 Radical Nephrectomy 0.25 0.22–0.28  < 0.001 0.311 0.264–0.366  < 0.001
Radiotherapy       
 No/unknown Reference      
 Yes 3.16 1.86–5.34  < 0.001    
Chemotherapy       
 No/Unknown Reference      
 Yes 3.48 2.46–4.94  < 0.001    
 Tumors number 1.27 1.21–1.33  < 0.001 1.192 1.136–1.249  < 0.001
Marriage       
 No Reference    Reference   
 Married 0.67 0.61–0.73  < 0.001 0.807 0.731–0.891  < 0.001
 Tumor size 1.001 1.001–1.002  < 0.001 1.002 1.001–1.004 0.003
  1. aOther includes Asian/Pacific Islander, American Indian/Alaskan Native;
  2. bOthers includes the pathological type of RCC is not known
  3. cLocal excision includes cryosurgery, thermal ablation, laser excision