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Table 1 Clinicopathological characteristics of patients with RCC

From: A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

  Total
N = 10,595
Training cohort
N = 7233
Validation cohort
N = 3024
p
Age 73.5 (6.73) 73.5 (6.69) 73.5 (6.83) 0.7
Race     0.4
 White 8300 (80.9%) 5847 (80.8%) 2453 (81.1%)  
 Black 1132 (11.0%) 815 (11.3%) 317 (10.5%)  
 Othera 825 (8.04%) 571 (7.89%) 254 (8.40%)  
Sex     0.4
 Male 6406 (62.5%) 4498 (62.2%) 1908 (63.1%)  
 Female 3851 (37.5%) 2735 (37.8%) 1116 (36.9%)  
Marriage     0.5
 No 4026 (39.3%) 2856 (39.5%) 1170 (38.7%)  
 Married 6231 (60.7%) 4377 (60.5%) 1854 (61.3%)  
Year of diagnosis     0.06
 2010–2013 4815 (46.9%) 3352 (46.3%) 1463 (48.4%)  
 2014–2017 5442 (53.1%) 3881 (53.7%) 1561 (51.6%)  
Histologictype     0.5
 Clear cell 5539 (54.0%) 3932 (54.4%) 1607 (53.1%)  
 Papillary 1658 (16.2%) 1173 (16.2%) 485 (16.0%)  
 Chromophobe 578 (5.64%) 407 (5.63%) 171 (5.65%)  
 Otherb 2482 (24.2%) 1721 (23.8%) 761 (25.2%)  
Laterality     1
 Left 4996 (48.7%) 3523 (48.7%) 1473 (48.7%)  
 Right 5261 (51.3%) 3710 (51.3%) 1551 (51.3%)  
T stage     0.9
 T1a 6309 (61.5%) 4452 (61.6%) 1857 (61.4%)  
 T1b 2907 (28.3%) 2045 (28.3%) 862 (28.5%)  
 T2a 764 (7.45%) 538 (7.44%) 226 (7.47%)  
 T2b 277 (2.70%) 198 (2.74%) 79 (2.61%)  
Grade     0.7
 I 993 (9.68%) 715 (9.89%) 278 (9.19%)  
 II 3923 (38.2%) 2782 (38.5%) 1141 (37.7%)  
 III 1846 (18.0%) 1293 (17.9%) 553 (18.3%)  
 IV 177 (1.73%) 123 (1.70%) 54 (1.79%)  
 Unknown 3318 (32.3%) 2320 (32.1%) 998 (33.0%)  
Surgery     0.044
 No 2040 (19.9%) 1387 (19.2%) 653 (21.6%)  
 Local excisionc 1446 (14.1%) 1035 (14.3%) 411 (13.6%)  
 Partial Nephrectomy 2973 (29.0%) 2119 (29.3%) 854 (28.2%)  
 Radical Nephrectomy 3798 (37.0%) 2692 (37.2%) 1106 (36.6%)  
Chemotherapy     0.9
 No/unknown 10,182 (99.3%) 7179 (99.3%) 3003 (99.3%)  
 Yes 75 (0.73%) 54 (0.75%) 21 (0.69%)  
Radiation     0.9
 No/unknown 10,223 (99.7%) 7210 (99.7%) 3013 (99.6%)  
 Yes 34 (0.33%) 23 (0.32%) 11 (0.36%)  
Total number of tumors 1.62 (0.84) 1.62 (0.84) 1.61 (0.82) 0.7
Tumor size 41.1 (27.2) 41.1 (26.9) 41.0 (28.1) 0.9
Survival months 47.4 (28.1) 47.3 (28.2) 47.8 (27.9) 0.4
Cancer-specific survival     0.8
 Dead 786 (7.66%) 558 (7.71%) 228 (7.54%)  
 Alive 9471 (92.3%) 6675 (92.3%) 2796 (92.5%)  
Overall survival     0.5
 Dead 2623 (25.6%) 1836 (25.4%) 787 (26.0%)  
 Alive 7634 (74.4%) 5397 (74.6%) 2237 (74.0%)  
  1. aOther includes Asian/Pacific Islander, American Indian/Alaskan Native;
  2. bOthers includes the pathological type of RCC is not known
  3. cLocal excision includes cryosurgery, thermal ablation, laser excision