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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

Fig. 2

Overexpression of circDYRK1A inhibits malignant phenotypes of GC cells in vitro. AGS cells were transduced with circDYRK1A overexpression vector and HGC-27 cells were transduced with sh-circDYRK1A. A Expression of circDYRK1A in AGS and HGC-27 cells determined by RT-qPCR. B The proliferation of AGS and HGC-27 cells detected by EdU assay. C The migration of AGS and HGC-27 cells detected by Transwell assay. D The invasion of AGS and HGC-27 cells detected by Transwell assay. The cell experiment was repeated three times. * p < 0.05 vs. sh-NC-treated HGC-27 cells or Vector-treated AGS cells

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