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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587

Fig. 5

In vitro study of the function of RNF185 overexpression in glioma cells U87 and DBTRG. A CCK8 assays showing the function of RNF185 overexpression in glioma cell number; B FACS determination of the function of RNF185 overexpression in glioma cell apoptosis rate; C wound healing assay studying the function of RNF185 overexpression in glioma cell migration; All experiments were conducted for three replicates; *pā€‰<ā€‰0.05, **pā€‰<ā€‰0.01

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