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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587

Fig. 1

CRISPR screening of E3 ligases reveals significantly changed genes (SCGs) in glioma cell line U87. A The workflow chat of CRISPR screening assays of E3 ligases in glioma U87 cells; B volcano plot showing the significantly enriched and lost genes; enriched genes were shown with red dots, and lost genes were shown with green dots; C reads counts in the first and 4th generation cells; D protein domain analysis of enriched and lost genes

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