Fig. 2
POR rs10954732 polymorphisms related to decreased HCC susceptibility and increased OS of HCC patients as well as enzyme activity for CYP2E1 in healthy subjects and HCC patients. a Univariate logistic regression analysis of the association between rs10954732 polymorphisms and the risk of HCC. b Kaplan–Meier curve for overall survival (OS) of HCC patients between the GG genotype and GA + AA genotypes in HCC patients. Biochemical data (c) and CYP2E1 activity (d) in subjects between GG genotype and A allele carriers in healthy subjects and HCC patients. A allele carriers, GA + AA genotypes. Normal, healthy subjects. HCC, hepatocellular carcinoma. AST transaminase, ALT alanine aminotransferase, Vmax maximum reaction velocity, CLint intrinsic clearance. Data are expressed as mean ± SEM, P value was calculated by Mann–Whitney U test