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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Macitentan attenuates cardiovascular remodelling in infant rats with chronic lung disease

Fig. 5

Right-to-left ventricle diameter ratio (A) and cardiomyocyte cross-sectional area (B) in N-P: normoxia (FiO2 0.21)-placebo (A n = 7, B n = 5); N-M: normoxia (FiO2 0.21)-macitentan (A n = 9, B n = 5); H-P: hyperoxia (FiO2 1.0)-placebo (A n = 7, B n = 5); and H-M: hyperoxia (FiO2 1.0)-macitentan (A n = 7, B n = 5). Data are expressed as vertical box plots with median, 10th, 25th, 75th, and 90th percentiles. * and # indicate significant difference to FiO2 0.21-placebo and FiO2 1.0-placebo, respectively, p < 0.05

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