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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Macitentan attenuates cardiovascular remodelling in infant rats with chronic lung disease

Fig. 3

Count of pulmonary vessels (A) and α-SMA content in the medial wall of the pulmonary arterioles (B) and in N-P: normoxia (FiO2 0.21)-placebo (A n = 6, B n = 6); N-M: normoxia (FiO2 0.21)-macitentan (A n = 9, B n = 8); H-P: hyperoxia (FiO2 1.0)-placebo (A n = 5, B n = 6); and H-M: hyperoxia (FiO2 1.0)-macitentan (A n = 5, B n = 7). Data are expressed as vertical box plots with median, 10th, 25th, 75th, and 90th percentiles. * and # indicate significant difference to FiO2 0.21-placebo and FiO2 1.0-placebo, respectively (p < 0.05)

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