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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling

Fig. 1

Expression of mPRα in tissue samples. A The mRNA expression of mPRα in 483 lung adenocarcinoma (LUAD) tissue samples and 347 noncancerous tissue samples according to TCGA database. B Cases from the TCGA-LUAD database were divided into two groups using the best cutoff of mPRα expression. The correlation between mPRα expression and the overall survival in patients with LUAD was analyzed by KMPLOT (https://kmplot.com/analysis/). C The mRNA expression of mPRα was determined in 20 paired LUAD and adjacent noncancerous tissue samples using real-time PCR. D The protein content and distribution of mPRα were determined in LUAD and adjacent noncancerous tissue samples using immunohistochemical (IHC) staining. E The protein content and distribution of mPRα were determined in LUAD and adjacent noncancerous tissue samples using Immunoblotting. F The CD31-MVD was determined in LUAD tissues samples with a high or low mPRα level. **P < 0.01, ***P < 0.005

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