Skip to main content

Table 3 Association between TXNIP cg19693031 methylation and fasting blood glucose stratified by GLUT1 rs841853 genotypes

From: Interaction between a diabetes-related methylation site (TXNIP cg19693031) and variant (GLUT1 rs841853) on fasting blood glucose levels among non-diabetics

 

rs841853-CC

rs841853-CA + AA

β

p-value

β

p-value

TXNIP cg19693031 (ref: ≥ Q3)

 Q2–Q3

0.8082

0.255

− 1.1672

0.160

 Q1–Q2

1.6930

0.022

0.0322

0.969

 < Q1

2.2190

0.004

0.1037

0.905

P for trend

 

0.002

 

0.491

Sex (ref: Women)

 Men

2.5831

 < .001

2.2765

0.001

Age

0.1863

 < .001

0.1980

 < .001

  1. TXNIP thioredoxin-interacting protein, GLUT1 glucose transporter 1, β beta coefficient, ref reference
  2. Adjusted for body mass index, cigarette smoking, alcohol drinking, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, hypertension, regular exercise, vegetarian diet, and coffee and tea intake
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us