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Table 1 Demographic characteristics of the study participants based on GLUT1 rs841853 genotypes (CC and CA + AA)

From: Interaction between a diabetes-related methylation site (TXNIP cg19693031) and variant (GLUT1 rs841853) on fasting blood glucose levels among non-diabetics

  rs841853-CC rs841853-CA + AA p-value
(n = 735) (n = 565)
Fasting blood glucose (mg/dL) 92.07  ± 7.78 91.62  ± 7.14 0.278
TXNIP cg19693031 (β) 0.7716 ± 0.05 0.7631 ± 0.05 0.002
TXNIP cg19693031 quartiles    0.005
 Q3 (β ≥ 0.800918) 210 (28.57) 117 (20.71)  
 Q2–Q3 (0.769992 ≤ 0.800918) 187 (25.44) 140 (24.78)  
 Q1–Q2 (0.738592 ≤ 0.769992) 168 (22.86) 158 (27.96)  
 Q1 (β < 0.738592) 170 (23.13) 150 (26.55)  
Sex    0.309
 Women 385 (52.38) 312 (55.22)  
 Men 350 (47.62) 253 (44.78)  
Age (years) 48.87 ± 11.03 48.22 ± 11.06 0.288
BMI (kg/m2) 23.95 ± 3.36 24.31 ± 3.75 0.071
Cigarette smoking    0.191
 No 559 (76.05) 447 (79.12)  
 Yes 176 (23.95) 118 (20.88)  
Alcohol drinking    0.889
 No 667 (90.75) 514 (90.97)  
 Yes 68 (9.25) 51 (9.03)  
Triglyceride (mg/dL) 112.56 ± 95.94 112.60 ± 103.11 0.994
HDL-C (mg/dL) 55.96 ± 14.27 54.42 ± 13.70 0.051
LDL-C (mg/dL) 122.67 ± 32.36 123.38 ± 33.55 0.699
Hypertension    0.294
 No 603 (82.04) 476 (84.25)  
 Yes 132 (17.96) 89 (15.75)  
Regular exercise    0.709
 No 420 (57.14) 317 (56.11)  
 Yes 315 (42.86) 248 (43.89)  
Tea intake    0.460
 No 451 (61.36) 358 (63.36)  
 Yes 284 (38.64) 207 (36.64)  
Coffee intake    0.997
 No 471 (64.08) 362 (64.07)  
 Yes 264 (35.92) 203 (35.93)  
Vegetarian diet    0.405
 No 671 (91.29) 588 (92.57)  
 Yes 64 (8.71) 49 (7.43)  
  1. Minimum and maximum TXNIP cg19693031 β = 0.510186 and 0.918557, respectively
  2. Continuous variables are represented by mean ± SD and categorical variables by n (%)
  3. GLUT1 glucose transporter 1, SD standard deviation, β beta-value, TXNIP thioredoxin-interacting protein, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol