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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Methotrexate-loaded nanoparticles ameliorate experimental model of autoimmune arthritis by regulating the balance of interleukin-17-producing T cells and regulatory T cells

Fig. 1

Characteristics of MTX-NPs. a Schematic of MTX-NP synthesis. b Size distribution, zeta-potential value, and TEM image of MTX-loaded nanoparticles. c MTX release profile of MTX-NPs. d Toxicological analysis of MTX-NPs in plasma. Plasma level of hepatotoxicity biomarker, aspartate aminotransferase (AST) and alanine aminotransferase (ALT). e Creatinine concentration, biomarker for kidney function. Error bar represents mean ± S.D. (n = 3). **P < 0.01 vs. control group

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