Fig. 7

Correlation of LPRS with clinicopathological features, genomic alterations and TIME patterns in TCGA cohort. A An overview of the correspondence between LPRS and other features of LGG patients. B Alluvial diagram showed the attribute changes of LLPS subtypes, WHO grade, immunity subtypes and LPRS. C Correlation between LPRS and the known cancer hallmarks. D Correlation of LPRS with TMB, mutation counts, and copy number burdens at focal and arm levels. E Correlation between LPRS and the ssGSEA Z-scores of 29 immune signatures. F Correlation of LPRS with immune scores, stromal scores, ESTIMATE scores and tumor purity. * P < 0.05, ** P < 0.01, and *** P < 0.001