Fig. 4

Visualization of the gene expression pattern of HSCs based on bulk RNA-sequencing data from dataset GSE154170. Kruskal-Wallis test examined differences in gene expression among 4 groups of mouse samples which includes: isolates of quiescent HSC, isolates of HSC from bile duct-ligated (BDL) mice biliary fibrosis model, HSC isolates from mice treated with 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) diet biliary fibrosis model, and isolates of HSC-derived CAF from intrahepatic cholangiocarcinoma (CCA) model. P < 0.05 was considered as statistically significant