Fig. 8

miR-875-5p inhibited tumour formation in vivo. A Xenograft tumours were obtained from different groups of nude mice injected with MKN-45 cells transfected with miR-875-5p NC and miR-875-5p mimics. B The tumour growth curve and tumour weight were significantly different between the miR-875-5p mimic group and the miR-875-5p NC group. C The expression of USF2 in xenograft tumours was determined by immunohistochemistry. D Proposed model of miR-875-5p regulating USF2 and affecting the TGF-β signalling pathway. *P < 0.05; Data expressed as mean ± SD