Fig. 3From: Good performance of the criteria of American College of Medical Genetics and Genomics/Association for Molecular Pathology in prediction of pathogenicity of genetic variants causing thoracic aortic aneurysms and dissectionsKaplan–Meier analysis of event free survival in TAAD probands with variants classified as A P/LP by ACMG but not by ClinVar (ACMG-CV P/LP) vs. reference group (REF, Log-Rank Chi- square 8.32, p = 0.0039); B P/LP pathogenic by both ClinVar and ACMG (CV P/LP) vs. P/LP pathogenic by ACMG alone (Log-Rank Chi- square 1.016, p = 0.90); C P/LP by ClinVar alone vs. reference group (Log-Rank Chi-square 5.18, p = 0.023), D B/LB by ACMG alone (ACMG-CV B/LB) vs. reference group (REF, Log-Rank Chi- square 0,028, p = 0.87)Back to article page