Fig. 9
From: Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomes
Validation of the pathway-based clustering method in a single cell RNA-Seq (scRNA-seq) dataset. A Clustering of 4371 malignant cells and 2580 non-malignant cells by the tSNE algorithm [21]. B Hierarchical clustering based on the enrichment scores of the 14 pathways identifies three subtypes of 6951 single cells from 12 sarcoma patients. C Distribution of the 6951 single cells in the three subtypes. Comparisons of immune signature scores (D), expression levels of DDR genes (E), and stemness scores (F) among the three subtypes