Fig. 5
From: Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomes
Comparisons of somatic mutation profiles among the sarcoma subtypes in TCGA-SARC. A 6 genes showing significantly different mutation frequencies among the sarcoma subtypes. B The genes showing significantly higher mutation frequencies in Imm-C than in DDR-C and Str-C (Fisher’s exact test, P < 0.05, OR > 4.0). *P < 0.05, **P < 0.01, ***P < 0.001. C The genes with higher mutation frequencies in Imm-C than in DDR-C and Str-C and their mutations associated with elevated enrichment levels of CD8 + T cells and/or immune cytolytic activity (one-tailed Mann–Whitney U test, P < 0.05)