Fig. 2
From: Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomes
Comparisons of immune, stromal and DDR signatures among the sarcoma subtypes. Comparisons of immune signature scores (A), the ratios of immune-stimulatory to immune-inhibitory signatures (CD8 + /CD4 + regulatory T cells) (B), stromal scores (C), EMT scores (D), the expression levels of seven DDR genes (E), and tumor purity (F) among the sarcoma subtypes. The immune scores, stomal scores, and tumor purity were evaluated by ESTIMATE [16]. The EMT scores are the ssGSEA scores [28] of its marker genes. The one-tailed Mann–Whitney U test or two-tailed Student’s t test P-values are shown. EMT: epithelial-to-mesenchymal transition. *P < 0.05, **P < 0.01, ***P < 0.001