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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Circular RNA circCSPP1 promotes the occurrence and development of colon cancer by sponging miR-431 and regulating ROCK1 and ZEB1

Fig. 6

CircCSPP1 upregulates cyclin D1/CDK4/RB signaling pathway in colon cancer. Colon cancer cells were treated with pcDNA3.1-circCSPP1, pcDNA3.1-circCSPP1 plus miR-431 mimics or pcDNA3.1-circCSPP1 plus ROCK1 shRNA. A, B Western blot was used to detect the expressions of cell cycle-related proteins (cyclin D1, CDK4, Rb) and EMT related protein (Snail, E-cadherin) in each group. C The potential mechanism by which circCSPP1 regulated the progression of colon cancer was presented. N = 3

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Journal of Translational Medicine

ISSN: 1479-5876

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