Fig. 1From: Evaluation of exosomal non-coding RNAs in cancer using high-throughput sequencingBiogenesis mechanism of exosomes, which starts with the development of the endosome and then forms multivesicular bodies (MVBs). MVBs can both integrate with lysosomes for degradation or fuse with the cellular membrane to release exosomes. These processes can happen by both ESCRT-dependent and ESCRT-independent pathwaysBack to article page