Fig. 3

GDF11 inhibited NLRP3 inflammasome activation and neointimal hyperplasia in vivo. A, B Proteins related to NLRP3 inflammasome activation (NLRP3, Casp1 p20, and IL-1β) were detected by Western blotting. C Representative cross-sections with hematoxylin and eosin (HE) staining from different groups (top scale bar represents 200 µm; bottom scale bar represents 50 µm). D–F Quantitative analysis of the neointimal area, the ratio of neointima to media area and the medial area in different groups. * p < 0.05 vs. the control group; # p < 0.05 vs. the BI group and the BI + Ad–GFP group