Fig. 15
From: Ground truth labels challenge the validity of sepsis consensus definitions in critical illness
Comparison of clinical criteria to ground truth labels for detection of the first sepsis episode. Sepsis onset in our 761 complete encounters was determined according to clinical criteria (computer icon) for Sepsis-1/2 (SIRS) and Sepsis-3 (SOFA ≥ 2). This point was compared to the first occurrence of a GTSQ label for sepsis (cross icon) considering either all three sepsis categories together or only severe sepsis and septic shock. a Identifies the four scenarios and according ratings, based on which agreement and test performance were evaluated. b Enumerates the results of the comparisons and the statistical measures of agreement and test performance. The 95% confidence intervals for all test performance measures were within ± 7%. PPV positive predictive value, NPV negative predictive value