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Table 2 Association between HDAC3 and FOXA1 expression and pathological features

From: FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma

Features Cases HDAC3
H-score
P value FOXA1
H-score
P value
Pathological type
 Serous 90 246.88 ± 48.12 0.06 244.82 ± 44.54 0.356
 Mucinous 7 192.31 ± 43.64 186.29 ± 59.14
 Clear cell 21 199.83 ± 57.52 208.89 ± 48.28
 Endometrioid 9 239.98 ± 40.04 236.12 ± 71.95
FIGO stage
 I–II 44 200.93 ± 54.42 0.007 202.55 ± 56.26  < 0.001
 III–IV 83 253.98 ± 41.30 252.01 ± 38.24
Lymphatic metastasis
 No 80 224.83 ± 41.34 0.002 222.98 ± 55.20 0.001
 Yes 47 253.95 ± 38.06 255.12 ± 34.60
Relapse
 Yes 61 263.89 ± 31.91  < 0.001 249.53 ± 42.76 0.002
 No 66 209.46 ± 54.51 221.33 ± 54.27
DOD
 Yes 43 266.52 ± 33.34  < 0.001 260.43 ± 32.87  < 0.001
 No 84 219.78 ± 53.70 221.79 ± 53.60
  1. Italic values indicate statistical significance (P < 0.05)
  2. HDAC3 Histone deacetylase 3, FOXA1 Fox protein A1, DOD die of disease