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Table 2 Association between HDAC3 and FOXA1 expression and pathological features

From: FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma

Features

Cases

HDAC3

H-score

P value

FOXA1

H-score

P value

Pathological type

 Serous

90

246.88 ± 48.12

0.06

244.82 ± 44.54

0.356

 Mucinous

7

192.31 ± 43.64

186.29 ± 59.14

 Clear cell

21

199.83 ± 57.52

208.89 ± 48.28

 Endometrioid

9

239.98 ± 40.04

236.12 ± 71.95

FIGO stage

 I–II

44

200.93 ± 54.42

0.007

202.55 ± 56.26

 < 0.001

 III–IV

83

253.98 ± 41.30

252.01 ± 38.24

Lymphatic metastasis

 No

80

224.83 ± 41.34

0.002

222.98 ± 55.20

0.001

 Yes

47

253.95 ± 38.06

255.12 ± 34.60

Relapse

 Yes

61

263.89 ± 31.91

 < 0.001

249.53 ± 42.76

0.002

 No

66

209.46 ± 54.51

221.33 ± 54.27

DOD

 Yes

43

266.52 ± 33.34

 < 0.001

260.43 ± 32.87

 < 0.001

 No

84

219.78 ± 53.70

221.79 ± 53.60

  1. Italic values indicate statistical significance (P < 0.05)
  2. HDAC3 Histone deacetylase 3, FOXA1 Fox protein A1, DOD die of disease