Fig. 5
From: FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma
Role of HDAC3 and FOXA1 in biological functions in vivo. A Xenograft experiments were performed to test and verify the role of HDAC3 and FOXA1 in tumor formation. The tumor curve is shown. Compared with the NC groups, the tumors in the HDAC3 overexpression group were significantly larger and heavier. In contrast, the tumors in the HDAC3 knockdown group were significantly smaller and lighter. B The tumor tissues were fixed in formalin, embedded in paraffin, and stained with H&E. IHC was performed to detect HDAC3 and FOXA1 expression. C H&E and IHC staining in lung tissues of xenografts. D Representative images of the peritoneal metastasis results