Fig. 3

Targeted proteomics study, bioinformatics analysis of COPA. PRM verification of COPA using unique peptides: A GITGVDLFGTTDAVVK and B CPLSGACYSPEFK. C Box-plot exhibiting protein levels of COPA in the three comparable groups. D PPI network analysis of all DEPs from cervical cancer (both AC and SCC) vs. healthy controls showed the first neighbour relationships (undirected) to COPA. E KEGG pathway analysis of the COPA and its first neighbour relationships. F Kaplan–Meier analyses for COPA (log-rank tests) based on TCGA database using the GEPIA2 software