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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages

Fig. 6

GM-CSF treatment leads to decreased expression of Mertk, Axl and Timd4 on mouse BM EBI macrophages. A Plot of Mertk versus FSC-H of DAPI−CD11b−Gr1− F4/80+macrophages in control and GM-CSF treated mice BM. B Quantitative analysis of Mertk+ percentage and the fluorescence intensity of Mertk. C Plot of Axl versus FSC-H of DAPI−CD11b−Gr1− F4/80+macrophages in control and GM-CSF treated mice BM. D Quantitative analysis of Axl+ percentage and the fluorescence intensity of Axl. E Plot of Timd4 versus FSC-H of DAPI−CD11b−Gr1− F4/80+macrophages in control and GM-CSF-treated mice BM. F Quantitative analysis of Timd4+ percentage and fluorescence intensity of Timd4. G Plot of Ter119 versus FSC-H of CD11b−Gr1− F4/80+macrophages in control and GM-CSF-treated mice BM. H Quantitative analysis of engulfment of Ter119+ Red blood cells of CD11b−Gr1− F4/80+macrophages in control and GM-CSF treated mice BM. *P < 0.05, ** P < 0.01 *** P < 0.001. N = 3–6

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