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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: From GWAS to drug screening: repurposing antipsychotics for glioblastoma

Fig. 2Fig. 2

Sensitivity of glioma cells to TMZ and candidate drugs. A The sensitivities of glioma cells to candidate drugs and TMZ ranking by mean sensitivity. (Ranking by mean sensitivity. × : mean value. CI: Confidence Interval) (B) Cells show significant higher sensitivities to two of candidate, Norcyclobenzaprine and Protriptyline (P = 5.89E−05 and 3.84E−05 respectively). C, D Heatmap of gene show significantly different expression in sensitive and non-sensitive cells to Norcyclobenzaprine and Protriptyline, respectively. The order of cell line follows the sensitivities of cells to Norcyclobenzaprine and Protriptyline from highest (left) to lowest (right)

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