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Table 2 Univariate and multivariate cox proportional hazard model for disease free survival (DFS) and overall survival (OS) in TNBC patients

From: CTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1

Variables Univariate analysis Multivariate analysis
DFS OS DFS OS
HR (95% CI) P a HR (95% CI) P a HR (95% CI) P a HR (95% CI) P a
Age (years)  
 ≤ 50 Reference   Reference      
 > 50 0.65 (0.38–1.11) 0.114 0.95 (0.50–1.81) 0.870     
Tumor size  
 ≤ 2 cm Reference   Reference   Reference    
 > 2 cm 1.96 (1.10–3.50) 0.023 1.82 (0.90–3.67) 0.098 1.71 (0.95–3.07) 0.073   
Lymph nodes metastasis  
 No Reference   Reference   Reference   Reference  
 Yes 1.82 (1.08–3.07) 0.026 2.00 (1.05–3.84) 0.036 1.65 (0.97–2.79) 0.065 1.85 (0.96–3.55) 0.066
Grade  
 I + II Reference   Reference      
 III 1.50 (0.85–2.65) 0.164 1.75 (0.85–3.62) 0.130     
Lymphovascular invasion      
 No Reference   Reference      
 Yes 1.66 (0.98–2.81) 0.057 1.47 (0.77–2.81) 0.240     
CTPS1 expression  
 Low Reference   Reference   Reference   Reference  
 High 1.97 (1.10–3.55) 0.010 2.49 (1.20–5.15) 0.014 1.90 (1.07–3.37) 0.029 2.34 (1.13–4.84) 0.023
  1. HR hazard ratio, CI confidence interval, DFS disease free survival, OS overall survival
  2. aThe P value was adjusted by the univariate Cox proportional hazard regression model
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Journal of Translational Medicine

ISSN: 1479-5876

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