Fig. 3
CTPS1 promotes TNBC tumor growth in vivo. a Images of xenograft tumors from groups of BALB/c-nude mice 4 weeks after the subcutaneous injection of stable CTPS1 knockdown MDA-MB-231 cells (shCTPS1) or control cells (shCtrl). b Tumor volume was calculated according to the formula: (length × width2)/2. c Tumor weight in nude mice of shCTPS1 and shCtrl group was assessed at day 28. d Hematoxylin–eosin (HE) staining and immunohistochemistry for proliferation marker Ki67 in xenograft tumors. ** p < 0.01, *** p < 0.001