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Table 4 Heterogeneity test of 20 serum 25OHD genetic variants in MS GWAS dataset

From: Mendelian randomization study updates the effect of 25-hydroxyvitamin D levels on the risk of multiple sclerosis

Method

MR-Egger intercept

Q

Q_df

Q_pval

MR Egger

29.446

18

0.043

Inverse variance weighted

30.614

19

0.044

  1. p < 0.05 is set as the significant threshold. Q_pval = 0.04 represents significant heterogeneity