Fig. 6

WGCNA of histological grade-related module. a Topological overlap matrix plot of the 1970 gene network. Genes in the rows and columns are sorted by the clustering tree in lighter color and show higher overlap. b Module—trait relationships between module genes and clinical features of IMPA. c GS in modules related to tumor grades. The green module has the highest GS (p  = 1.5e−107). d A scatterplot of MM vs. GS module membership (MM) in the green module. There is a strong positive association between MM and GS in this module