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Table 2 MR results of periodontal disease on risk of COVID-19 susceptibility and severity

From: Periodontal disease increases the host susceptibility to COVID-19 and its severity: a Mendelian randomization study

Outcomes

Methods

OR

(95% CI)

P value

COVID-19 susceptibility

(COVID-19 vs. population)

Inverse variance weighted

1.024

1.004–1.045

0.017

MR Egger

1.064

0.933–1.214

0.418

Weighted median

1.029

1.003–1.055

0.024

Weighted mode

1.031

0.998–1.066

0.135

COVID-19 severity

(Hospitalized vs. population)

Inverse variance weighted

1.025

1.001–1.049

0.039

MR Egger

1.053

0.893–1.240

0.580

Weighted median

1.030

1.003–1.058

0.027

Weighted mode

1.046

0.999–1.094

0.139

COVID-19 severity

(Very severe respiratory confirmed vs. not hospitalized)

Inverse variance weighted

0.964

0.797–1.166

0.711

MR Egger

1.305

0.356–4.784

0.713

Weighted median

1.004

0.784–1.287

0.967

Weighted mode

1.087

0.789–1.499

0.652

  1. OR odds ratio, 95% CI 95% confidence interval
  2. Significant associations (P value < 0.05) are highlighted in bold format