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Table 3 Univariate COX regression analysis of overall survival

From: Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness

Variables

P-value

Risk ratio

95% CI

Sex (male, female)

0.464

1.444

(0.54, 3.862)

Age (≤ 50, > 50)

0.805

0.995

(0.957, 1.035)

Tumor location (tongue, gingiva, buccal mucosa, palate, lower lip, jaw, others)

0.803

0.964

(0.725, 1.283)

Tumor size (T1–T4)

0.63

1.128

(0.69, 1.844)

Lymph node metastasis

0.977

1.01

(0.522, 1.954)

Clinical stage (I, II, III, IV)

0.633

1.122

(0.7, 1.798)

Pathological grade

0.96

0.98

(0.434, 2.213)

Local infiltration

0.816

0.881

(0.303, 2.562)

α-SMA in tumor stroma (low, high)

0.928

0.955

(0.35, 2.603)

LOX in tumor stroma ( low, high)

0.025

10.088

(1.332, 76.419)

  1. CI confidence interval
  2. Bold values signify P-value < 0.05.