Fig. 1From: SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effectSIRT5 is downregulated and associated with the prognosis of patients with ccRCC. A SIRT5 expression in tumor and normal tissues in TCGA-KIRC dataset. B SIRT5 expression in 72 paired ccRCC tissues from TCGA-KIRC cohort. SIRT5 expression levels were compared in groups stratified by different clinicopathological parameters: TNM stage (C–E), tumor grade (F) and pathological stage (G). H Kaplan–Meier analysis of OS of patients stratified by SIRT5 expression in TCGA-KIRC dataset. Cluster dendrograms (I), soft thresholds (J) and module-trait relationships (K) were analysed using WGCNA. L GO functional enrichment analysis. M KEGG pathway analysisBack to article page