Association between pulse pressure, systolic blood pressure and the risk of rapid decline of kidney function among general population without hypertension: results from the China health and retirement longitudinal study (CHARLS)

Table 3 Association between BP category and the risk of rapid decline of eGFR, fully adjusted and age-stratified

Variables	In total (n, %)	Overall		Age 45–54 years		Age 55–64 years		Age ≥ 65 years
Variables	In total (n, %)	Adjusted OR	P value	Adjusted OR	P value	Adjusted OR	P value	Adjusted OR	P value
PP category
Normal: < 60 mmHg	4057(89.5)	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
High: ≥ 60 mmHg	477(10.52)	1.34(1.02–1.75)	0.036	1.65(0.83, 3.29)	0.153	1.23(0.79–1.90)	0.364	1.51(1.00–2.27)	0.051
SBP category
Medium: 120–129 mmHg	1187(26.2)	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Low: < 120 mmHg	2398(52.9)	1.28(1.03–1.59)	0.025	1.65(1.13–2.43)	0.010	1.05(0.76–1.46)	0.769	1.15(0.73–1.81)	0.550
High: 130–139 mmHg	949(20.9)	1.32(1.02–1.71)	0.032	1.34(0.81–2.22)	0.255	1.41(0.95–2.07)	0.084	1.26(0.78–2.05)	0.345
DBP category
Low: < 60 mmHg	531(11.7)	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Medium: 60–74 mmHg	2502(55.2)	0.95(0.72–1.25)	0.706	1.10(0.67–1.82)	0.708	0.99(0.62–1.59)	0.974	0.78(0.48–1.27)	0.321
High: 75–89 mmHg	1501(33.1)	0.83(0.62–1.12)	0.226	0.81(0.48–1.38)	0.446	0.96(0.58–1.59)	0.888	0.77(0.44–1.34)	0.349

Adjusted for age, gender, smoke, drink, BMI, HbA1c, LDL, UA, eGFR at baseline
BP blood pressure, PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure, OR odds ratio, Ref. reference, BMI body mass index, HbA1c hemoglobin A1c, LDL low-density lipoprotein, UA uric acid, eGFR estimated glomerular filtration rate

ISSN: 1479-5876