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Table 3 Association between BP category and the risk of rapid decline of eGFR, fully adjusted and age-stratified

From: Association between pulse pressure, systolic blood pressure and the risk of rapid decline of kidney function among general population without hypertension: results from the China health and retirement longitudinal study (CHARLS)

Variables In total
(n, %)
Overall Age 45–54 years Age 55–64 years Age ≥ 65 years
Adjusted OR P value Adjusted OR P value Adjusted OR P value Adjusted OR P value
PP category
 Normal: < 60 mmHg 4057(89.5) Ref Ref Ref Ref Ref Ref Ref Ref
 High: ≥ 60 mmHg 477(10.52) 1.34(1.02–1.75) 0.036 1.65(0.83, 3.29) 0.153 1.23(0.79–1.90) 0.364 1.51(1.00–2.27) 0.051
SBP category
 Medium: 120–129 mmHg 1187(26.2) Ref Ref Ref Ref Ref Ref Ref Ref
 Low: < 120 mmHg 2398(52.9) 1.28(1.03–1.59) 0.025 1.65(1.13–2.43) 0.010 1.05(0.76–1.46) 0.769 1.15(0.73–1.81) 0.550
High: 130–139 mmHg 949(20.9) 1.32(1.02–1.71) 0.032 1.34(0.81–2.22) 0.255 1.41(0.95–2.07) 0.084 1.26(0.78–2.05) 0.345
DBP category
 Low: < 60 mmHg 531(11.7) Ref Ref Ref Ref Ref Ref Ref Ref
 Medium: 60–74 mmHg 2502(55.2) 0.95(0.72–1.25) 0.706 1.10(0.67–1.82) 0.708 0.99(0.62–1.59) 0.974 0.78(0.48–1.27) 0.321
 High: 75–89 mmHg 1501(33.1) 0.83(0.62–1.12) 0.226 0.81(0.48–1.38) 0.446 0.96(0.58–1.59) 0.888 0.77(0.44–1.34) 0.349
  1. Adjusted for age, gender, smoke, drink, BMI, HbA1c, LDL, UA, eGFR at baseline
  2. BP blood pressure, PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure, OR odds ratio, Ref. reference, BMI body mass index, HbA1c hemoglobin A1c, LDL low-density lipoprotein, UA uric acid, eGFR estimated glomerular filtration rate