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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: TRIM38 triggers the ubiquitination and degradation of glucose transporter type 1 (GLUT1) to restrict tumor progression in bladder cancer

Fig. 6

GLUT1 inhibitor (BAY-876) was effective to inhibit the progression of TRIM38low/− bladder cancer. a The half maximal inhibitory concentration (IC50) values of BAY-876 (GLUT1 inhibitor) in BLCA cell lines (T24, EJ and 5637). b–d BAY-876 could suppress the cell growth of BLCA cells in a dose-dependent manner. e Representative image inhibited that BAY-876 could inhibit the tumor volumes derived from TRIM38-KO cells relative to tumors derived from control cells. f The tumor volumes were detected and recorded at the indicated timepoints and the growth curve was generated. g Tumors were resected and weighed to compare the differences in the indicated groups

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