Fig. 8From: Promotion of microRNA-146a by histone deacetylase 4 silencing contributes to radiosensitization of esophageal carcinomaThe mechanism graph of the regulatory network of HDAC4 in EC. HDAC4 overexpression occurs in radioresistant EC cells. HDAC4 promotes cell proliferation and inhibits apoptosis of EC cells by downregulating miR-146a expression and elevating IRAK1 expression, leading to promoted radioresistance of EC cellsBack to article page