Fig. 4

Correlations between the expression levels of host genes and the microbiome composition. a The relationship between the abundance of some selected bacteria enriched differently between normal and tumor tissues and the pathways of genes expressed in CRC tissues estimated by ssGSEA. b Correlation between the composition of cell types deconvoluted by xCell and the bacteria used in a. The color of the squares indicates the magnitude of the correlation according to the scales indicated in the bar on the right side, and asterisks indicate the significance of the correlation (***P < 0.001, **P < 0.01, *P < 0.05)