Fig. 3

Single and multi-gene expression visualization across all tissues, obtained from GTEx. 3A: Single expression visualization of EFNA5 gene, as the nearest gene, is shown. The Y-axis shows the expression density of EFNA5 measured as linear count of transcript per million (TPM), and the X-axis shows the tissues sorted as a decrease in the median of TPM. Box plots are shown as median and 25th and 75th percentiles; points are displayed as outliers if they are above or below 1.5 times the interquartile range. 3B: A heat map of multi-gene expression visualization for EFNA5, FBXL17, and FER genes is shown. The genes and tissues are clustered using hierarchical clustering. The expression level of the gene per tissue is color-coded according to the linear count of TPM as indicated by the legend. The red box shows sub-clusters of high expression levels of the three genes in secretory tissues, including the minor salivary gland