Fig. 9

Propofol represses circNOLC1 expression by targeting STAT3. A–E The MDA-MB-231 and MDA-MB-468 cells were treated with propofol. A and B The expression of circNOLC1 was determined by qPCR. C The levels of STAT3 were detected by Western blot analysis. D and E The enrichment of STAT3 on circNOLC1 promoter was measured by ChIP assays. F and G The MDA-MB-231 and MDA-MB-468 cells were treated with STAT3 siRNA. The expression of circNOLC1 was determined by qPCR. H and I The MDA-MB-231 and MDA-MB-231 cells were treated with propofol with or without STAT3 overexpressing plasmid. The expression of circNOLC1 was determined by qPCR. **P < 0.01