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Fig. 9 | Journal of Translational Medicine

Fig. 9

From: The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling

Fig. 9

Propofol represses circNOLC1 expression by targeting STAT3. AE The MDA-MB-231 and MDA-MB-468 cells were treated with propofol. A and B The expression of circNOLC1 was determined by qPCR. C The levels of STAT3 were detected by Western blot analysis. D and E The enrichment of STAT3 on circNOLC1 promoter was measured by ChIP assays. F and G The MDA-MB-231 and MDA-MB-468 cells were treated with STAT3 siRNA. The expression of circNOLC1 was determined by qPCR. H and I The MDA-MB-231 and MDA-MB-231 cells were treated with propofol with or without STAT3 overexpressing plasmid. The expression of circNOLC1 was determined by qPCR. **P < 0.01

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