Fig. 8

The overexpression of STAT3 rescues circNOLC1 depletion-attenuated proliferation and cancer stem cell activity of breast cancer. A–E The MDA-MB-231 and MDA-MB-468 cells were treated with circNOLC1 shRNAs with or without STAT3 overexpressing plasmid. A and B The cell viability was detected by CCK-8 assays. C The sphere formation ability was determined by sphere formation assays. D and E The SP ration was identified by Hoechst 33342 staining using flow cytometry analysis. **P < 0.01