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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling

Fig. 6

MiR-365a-3p targets STAT3 in breast cancer cells. A The predicted binding sites of STAT3 and miR-365a-3p. BD The MDA-MB-231 and MDA-MB-468 cells were treated with miR-365a-3p mimic. B The levels of miR-365a-3p were validated by qPCR. C and D The luciferase activities of STAT3 were determined by luciferase reporter gene assays. E The MDA-MB-231 and MDA-MB-468 cells were treated with circNOLC1 overexpression plasmid and miR-365a-3p mimic. The protein levels of STAT3 were determined by Western blot analysis. F The levels of STAT3 were examined by qPCR in clinical breast cancer tissues (n = 30). **P < 0.01

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