Skip to main content
Fig. 4 | Journal of Translational Medicine

Fig. 4

From: The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling

Fig. 4

CircNOLC1 function as a ceRNA for miR-365a-3p. A The predicted binding sites of circNOLC1 and miR-365a-3p. BD The MDA-MB-231 and MDA-MB-468 cells were treated with miR-365a-3p mimic. B The levels of miR-365a-3p were validated by qPCR. C and D The luciferase activities of circNOLC1 were determined by luciferase reporter gene assays. E The interaction between circNOLC1 and miR-365a-3p was confirmed using RNA pull down analysis. F The MDA-MB-231 and MDA-MB-231 cells were treated with circNOLC1 shRNAs. The levels of miR-365a-3p were tested by qPCR. G The levels of miR-365a-3p were examined by qPCR in clinical breast cancer tissues (n = 30). **P < 0.01

Back to article page