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Table 4 Estimated power calculation for CRP reduction between 50 and 75% in the active treatment group is shown, evaluated with 3 different standard deviation (SD) values

From: Interleukin-1 blockade in cardiac sarcoidosis: study design of the multimodality assessment of granulomas in cardiac sarcoidosis: Anakinra Randomized Trial (MAGiC-ART)

Power analysis

CRP reduction

(estimated mean 7.64 mg/l)

N = 28

50%

55%

60%

65%

70%

75%

SD 3.37 mg/l

85%

91%

95%

97%

99%

 > 99%

SD 3.74 mg/l

77%

84%

90%

94%

97%

98%

SD 4.11 mg/l

69%

77%

84%

89%

93%

96%